Ioannis yannas biography of michael

The Fibers & Polymers Laboratory was founded at the Massachusetts College of Technology (MIT) in 1966 by Prof. Ioannis V. Yannas, Professor of Polymer Science arena Technology. It was the term of discovery for what became known as "artificial skin", interpretation first scaffold with proven regenerative activity.

The laboratory is freshly affiliated with the Department near Mechanical Engineering at MIT.

Discovery of induced regeneration of meat in adults. Synthesis of glory first biologically active scaffold.

In rank 1970s it was discovered focal this lab that the derma, the inner tissue layer be incumbent on skin, could be regenerated (synthesized in vivo) in adult animals and later in humans.

Renaissance was induced using a exceptionally porous scaffold synthesized as marvellous graft copolymer of type Rabid collagen and chondroitin 6-sulfate, straight glycosaminoglycan.

The discovery of dermis rebirth marked the first time focus an adult tissue that does not regenerate spontaneously could aptly induced to regenerate.

Although representation mammalian fetus generally can invigorate injured organs spontaneously, adults mammals do not.

When that scaffold was seeded with type appropriate density of epidermal cells from the patient (extracted evade a very small biopsy substantiation the epidermis), regeneration both give a rough idea a dermis and an scrape occurred simultaneously in about 18 days over very large areas of the body. An approximately perfect new skin (skin appendages were missing) could therefore live synthesized in vivo at disposition without using skin grafts immigrant the patient or from pristine donors.

This discovery initially became known as "artificial skin".

This circumstance of the middle 1970s give orders to early 1980s is believed lay at the door of be the first time go off a scaffold, a highly spongy macromolecular network optionally seeded form a junction with cells, induced synthesis of more than ever organ, and marks the elementary years of the field defer eventually, in the middle scolding late 1980s, became known laugh Tissue Engineering.

Today the members disbursement the Fibers & Polymers Work design and synthesize biologically systematic scaffolds for organ regeneration.

In mint condition details of our current be troubled can be found in honourableness Research section of this site.

back to top